# Usage examples

## Minimal example

The main function is `fit_cumhist()` that takes a data frame with time-series as a first argument. In addition, you need to specify the name of the column that codes the perceptual state (`state` argument) and a column that holds either dominance phase duration (`duration`) or its onset (`onset`). The code below fits data using Gamma distribution (default family) for a single run of a single participant. By default, the function fits cumulative history time constant but uses default fixed mixed state value (`mixed_state = 0.5`) and initial history values (`history_init = 0`).

    library(bistablehistory)

    data(br_singleblock)
    gamma_fit <- fit_cumhist(br_singleblock,
                             state="State",
                             duration="Duration",
                             refresh=0)

Alternatively, you specify onset of individual dominance phases that will be used to compute their duration.

    gamma_fit <- fit_cumhist(br_singleblock,
                            state="State",
                            onset="Time")

You can look at the fitted value for history time constant using `history_tau()`

    history_tau(gamma_fit)
    #> # A tibble: 1 x 3
    #>   Estimate `5.5%` `94.5%`
    #>      <dbl>  <dbl>   <dbl>
    #> 1    0.989  0.770    1.24

and main effect of history for both parameters of gamma distribution

    historyef(gamma_fit)
    #> # A tibble: 2 x 4
    #>   DistributionParameter Estimate `5.5%` `94.5%`
    #>   <fct>                    <dbl>  <dbl>   <dbl>
    #> 1 shape                    1.00   0.111    1.97
    #> 2 scale                    0.332 -0.741    1.31

The following model is fitted for the example above, see also companion vignette for details on cumulative history computation. \[Duration[i] \sim Gamma(shape[i], rate[i]) \\ log(shape[i]) = \alpha^{shape} + \beta^{shape}_H \cdot \Delta h[i] \\ log(rate[i]) = \alpha^{rate} + \beta^{rate}_H \cdot \Delta h[i] \\ \Delta h[i] = \text{cumulative_history}(\tau, \text{history_init})\\ \alpha^{shape}, \alpha^{rate} \sim Normal(log(3), 5) \\ \beta^{shape}_H, \beta^{rate}_H \sim Normal(0, 1) \\ \tau \sim Normal(log(1), 0.15)\]

## Passing Stan control parameters

You can pass Stan control parameters via `control` argument, e.g.,

    gamma_fit <- fit_cumhist(br_singleblock,
                            state="State",
                            duration="Duration",
                            control=list(max_treedepth = 15,
                                         adapt_delta = 0.99))

See Stan documentation for details (Carpenter et al. 2017).

## Run

By default, `fit_cumhist()` function assumes that the time-series represent a single run, so that history states are initialized only once at the very beginning. You can use `run` argument to pass the name of a column that specifies individual runs. In this case, history is initialized at the beginning of every run to avoid spill-over effects.

    gamma_fit <- fit_cumhist(br_single_subject,
                            state="State",
                            onset="Time",
                            run="Block")

## Experimental session

Experimental session specifies which time-series were measured together and is used to compute an average dominance phase duration that, in turn, is used when computing cumulative history: \(\tau_H = \tau \cdot <D>\), where \(\tau\) is normalized time constant and \(<D>\) is the mean dominance phase duration. This can be used to account for changes in overall alternation rate between different sessions (days), as, for example, participants new to the stimuli tend to “speed up” over the course of days (Suzuki and Grabowecky 2007). If you do not specify `session` parameter then a single mean dominance phase duration is computed for all runs of a single subject.

## Random effect

The `random_effect` argument allows you to specify a name of the column that codes for a random effect, e.g., participant identity, bistable display (if different displays were used for a single participant), etc. If specified, it is used to fit a hierarchical model with random slopes for the history effect (\(\beta_H\)). Note that we if random independent intercepts are used as prior research suggest large differences in overall alternation rate between participants (Brascamp et al. 2019).

Here, is the R code that specifies participants as random effect

    gamma_fit <-  fit_cumhist(kde_two_observers,
                              state="State",
                              duration="Duration",
                              random_effect="Observer",
                              run="Block")

And here is the corresponding model, specified for the shape parameter only as identical formulas are used for the rate parameter as well. Here, \(R_i\) codes for a random effect level (participant identity) and a non-centered parametrization is used for the pooled random slopes.

\[Duration[i] \sim Gamma(shape[i], rate[i]) \\ log(shape[i]) = \alpha[R_i] + \beta_H[R_i] \cdot \Delta h[i] \\ \Delta H[i] = \text{cumulative_history}(\tau, \text{history_init})\\ \alpha[R_i] \sim Normal(log(3), 5) \\ \beta_H[R_i] = \beta^{pop}_H + \beta^{z}_H[R_i] \cdot \sigma^{pop}_H\\ \beta^{pop}_H \sim Normal(0, 1) \\ \beta^{z}_H[R_i] \sim Normal(0, 1) \\ \sigma^{pop}_H \sim Exponential(1) \\ \tau \sim Normal(log(1), 0.15)\]

Identical approach is take for \(\tau\), if `tau=' "1|random"'` was specified and same holds for `mixed_state=' "1|random"'` argument, see below.

## Fixed effects

`fit_cumhist()` functions allows you to specify multiple fixed effect terms as a vector of strings. The implementation is restricted to:

- Only continuous (metric) independent variables should be used.
- A single value is fitted for each main effect, irrespective of whether a random effect was specified.
- You cannot specify an interaction either between fixed effects or between a fixed effect and cumulative history variable.

Although this limits usability of the fixed effects, these restrictions allowed for both a simpler model specification and a simpler underlying code. If you do require more complex models, please refer to companion vignette that provides an example on writing model using Stan directly.

You can specify custom priors (a mean and a standard deviation of a prior normal distribution) via `history_effect_prior` and `fixed_effects_priors` arguments. The former accepts a vector with mean and standard deviation, whereas the latter takes a named list in format .

Once fitted, you can use `fixef()` function to extract a posterior distribution or its summary for each effect.

## Cumulative history parameters

`fit_cumhist()` function takes three parameters for cumulative history computation (see also companion vignette):

- `tau` : a normalized time constant in units of mean dominance phase duration.
- `mixed_state` : value used for mixed/transition state phases, defaults to `0.5`.
- `history_init` : an initial value for cumulative history at the onset of each run. Defaults to `0`.

Note that although `history_init` accepts only fixed values either a single value used for both states or a vector of two. In contrast, both fixed and fitted values can be used for the other three parameters. Here are possible function argument values

- a single positive number for `tau` or single number within [0, 1] range for `mixed_state`. In this case, the value is used directly for the cumulative history computation, which is default option for `mixed_state`.
- `NULL` : a single value is fitted and used for all participants and runs. This is a default for `tau`.
- `'random'` : an independent tau is fitted for each random cluster (participant, displays, etc.). `random_effect` argument must be specified.
- `'1|random'` : values for individual random cluster are sampled from a fitted population distribution (pooled values). `random_effect` argument must be specified.

You can specify custom priors for each cumulative history parameter via `history_priors` argument by specifying mean and standard deviation of a prior normal distribution. The `history_priors` argument must be a named list, , e.g., `history_priors = list("tau"=c(1, 0.15))`.

Once fitted, you can use `history_tau()` and `history_mixed_state()`functions to obtain a posterior distribution or its summary for each parameter.

## Distribution family

`fit_cumhist` currently supports three distributions: `'gamma'`, `'lognormal'`, and `'normal'`.

### Gamma

\[Duration[i] \sim Gamma(shape[i], rate[i])\] For Gamma distribution independent linear models with a log link function are fitted for both shape and rate parameter. Priors for intercepts for both parameters are \(\alpha ~ Normal(log(3), 5)\).

### Log-normal

\[Duration[i] \sim LogNormal(\mu[i], \sigma)\] The \(\mu\) parameter is computed via a linear model with a log link function. Priors for the intercept are \(\alpha ~ Normal(log(3), 5)\). Prior for \(\sigma\) was \(\sigma \sim Exponential(1)\).

### Normal

\[Duration[i] \sim Normal(\mu[i], \sigma)\] The \(\mu\) parameter is computed via a linear model. Priors for the intercept are \(\alpha ~ Normal(3, 5)\). Prior for \(\sigma\) was \(\sigma \sim Exponential(1)\).

## Model comparison

Models fits can be compared via information criteria. Specifically, the log likelihood is stored in a `log_lik` parameter that can be directly using `loo::extract_log_lik()` function (see package (@ loo?)) or used to compute either a leave-one-out cross-validation (via `loo()` convenience function) or WAIC (via `waic()`). These are information criteria that can be used for model comparison the same way as Akaike (AIC), Bayesian (BIC), or deviance (DIC) information criteria. The latter can also be computed from log likelihood, however, WAIC and LOOCV are both preferred for multi-level models, see (Vehtari, Gelman, and Gabry 2017). The model comparison itself can be performed via `loo::loo_compare()` function of the `loo` package.

## Predicted values

You can predict durations for individual dominance phases via `predict()` function. You have an option of getting a summary (an average expected duration plus an optional credible interval) or computing predicted durations for every sample.

For summary statistics with 89% credible interval.

    predictions <- predict(gam_fit, summary = TRUE, probs = c((1-0.89)/2, 1 - (1-0.89)/2))

Predictions for every sample for full length time-series (invalid samples are filled with `NA`):

    prediction_samples <- predict(gam_fit, summary = FALSE, full_length = TRUE)

Predictions for every sample only for valid samples:

    prediction_samples <- predict(gam_fit, summary = FALSE, full_length = FALSE)

## Computing and using cumulative history

If you are interested in the cumulative history itself, you can extract from the fitted object via `predict_history()` function. Note that there are five different history types you can extract:

- `"1"`: cumulative history for the first perceptual state, i.e., state with index of 1.
- `"2"`: cumulative history for the second perceptual state, i.e., state with index of 2.
- `"dominant"`: for the state that is dominant during the following phase.
- `"suppressed"`: for the state that is suppressed during the following phase.
- `"difference"`: difference between cumulative histories (\(\Delta h = h_{suppressed} - h{dominant}\)), which is used in linear models.

    H <- predict_history(gam_fit, "difference")

Alternatively, you can skip fitting and compute history directly using predefined values via `compute_history()`.

    df <- compute_history(br_singleblock,
                          state="State",
                          duration="Duration",
                          tau=1,
                          mixed_state=0.5,
                          history_init=0)

## References

Brascamp, Jan W., Cheng Stella Qian, David Z. Hambrick, and Mark W. Becker. 2019. “Individual differences point to two separate processes involved in the resolution of binocular rivalry.” Journal of Vision 19 (12): 15. https://doi.org/10.1167/19.12.15.
Carpenter, Bob, Andrew Gelman, Matthew D. Hoffman, Daniel Lee, Ben Goodrich, Michael Betancourt, Marcus Brubaker, Jiqiang Guo, Peter Li, and Allen Riddell. 2017. “Stan : A Probabilistic Programming Language.” Journal of Statistical Software 76 (1). https://doi.org/10.18637/jss.v076.i01.
Suzuki, Satoru, and Marcia Grabowecky. 2007. “Long-term speeding in perceptual switches mediated by attention-dependent plasticity in cortical visual processing.” Neuron 56 (4): 741–53. https://doi.org/10.1016/j.neuron.2007.09.028.
Vehtari, Aki, Andrew Gelman, and Jonah Gabry. 2017. “Practical Bayesian model evaluation using leave-one-out cross-validation and WAIC.” Statistics and Computing 27 (5): 1413–32. https://doi.org/10.1007/s11222-016-9696-4.