Package: OneArm2stage
Title: Optimal One-Arm Two-Stage Phase II Design with Survival Endpoint
Version: 1.1.5
Authors@R: 
    c(person("Xiaomeng", "Yuan",  email="xiaomeng.yuan@stjude.org", role = c("aut", "cre")),
      person("Haitao", "Pan",  email="haitao.pan@stjude.org", role = c("aut")),
      person("Jianrong", "Wu",  email="jiwu@salud.unm.edu", role = c("aut"))
           )
Description: The proposed two-stage design can be used for single-arm phase II trial designs with 
    time-to-event endpoints, which is desirable for clinical trials on immunotherapies 
    among cancer patients. There're two advantages of the proposed approach: 1) It provides
    flexible choices of four underlying survival distributions and 2) the power of the design
    is more accurately calculated using exact variance in one-sample log-rank test. The package
    can be used for 1) planning the sample size; 2) conducting the interim and final analyses for
    the Go/No-go decisions. More details about the design method can be found in the paper: 
    Wu, J, Chen L, Wei J, Weiss H, Chauhan A. (2020). <doi:10.1002/pst.1983>. 
NeedsCompilation: no
Encoding: UTF-8
Repository: CRAN
RoxygenNote: 7.2.1
Imports: survival, utils, flexsurv, IPDfromKM
Suggests: knitr, rmarkdown, testthat (>= 3.0.0)
VignetteBuilder: knitr
Config/testthat/edition: 3
License: GPL (>= 3)
Depends: R (>= 3.5.0)
Packaged: 2022-11-30 17:48:57 UTC; xyuan86
Author: Xiaomeng Yuan [aut, cre],
  Haitao Pan [aut],
  Jianrong Wu [aut]
Maintainer: Xiaomeng Yuan <xiaomeng.yuan@stjude.org>
Date/Publication: 2022-12-01 21:20:02 UTC
Built: R 4.1.2; ; 2022-12-02 12:12:16 UTC; unix
