Package: GlobalFit
Type: Package
Title: Bi-Level Optimization of Metabolic Network Models
Version: 1.2
Date: 2016-08-12
Author: Daniel Hartleb
Maintainer: Daniel Hartleb <daniel.hartleb@hhu.de>
Description: Initial metabolic networks often inaccurately predict in-silico growth or non-growth if compared to in-vivo data. This package refines metabolic network models by making networks changes (i.e., removing, adding, changing reversibility of reactions; adding and removing biomass metabolites) and simultaneously matching sets of experimental growth and non-growth data (e.g., KO-mutants, mutants grown under different media conditions,...)
License: GPL-3
Depends: R (>= 2.12.0), sybil (>= 1.1.7), methods
Suggests: cplexAPI (>= 1.2.1)
NeedsCompilation: no
Packaged: 2016-08-12 08:27:50 UTC; daniel
Repository: CRAN
Date/Publication: 2016-08-12 12:36:23
Built: R 4.0.2; ; 2020-07-16 01:02:29 UTC; unix
